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As an inhibitor of NRF2, Keap1 recognizes and binds to the ETGE and DLG motifs of NRF2 via its Kelch repeat domain, thereby continuously suppressing and promoting the degradation of NRF2 [87]

Resection with or without adjuvant radiation therapy is usually considered for localized disease, with cytotoxic chemotherapy reserved for unresectable cases

Dietary NAD + could partially resolve SARS-CoV-2-induced dysregulated gene expression and mitochondrial metabolism 523

Unlike many medications with standardized dosing, Sermorelin protocols require individualization based on patient characteristics, treatment goals, and response patterns