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Tissue-Specific Distribution : The enhanced bioavailability allows for preferential accumulation in glutathione-dependent organs, particularly the liver for detoxification processes and the lungs for respiratory support against oxidative stress

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation

Furthermore, AC has been shown to exert vasorelaxant effects against noradrenaline (NA)-induced contractions in a time- and concentration-dependent manner, without affecting high K+-induced contractions