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These processes do not only depend on intracellular dynamics of hepatocytes, but are in part regulated by intercellular signaling between hepatocytes and immune cells such as the livers resident Kupffer cells (KCs) and recruited monocyte-derived macrophages (ms) 14
Follistatin-344: Myostatin Neutralisation and ActRIIB Biology Follistatin is a secreted glycoprotein that binds and neutralises members of the TGF- superfamily particularly myostatin (GDF-8), activin-A, activin-B, and GDF-11 by steric occlusion of their type II receptor (ActRIIB) binding surfaces
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